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Keith Duce 44902 Virginia Avenue New Rochelle, NY 02334 (212) 678-1276 | |
| summary of qualifications | |
| BIOINFORMATICS SCIENTIST | |
- Vast experience in protein sequencing and analysis using BLAST, genefinder, ORFfinder, and Grail. - Gene discovery, including protein domain identifications, EST blast. Unfinished sequence database mining. - Proficient in structure-function relationship, both in experiments and molecular modeling based on three-dimensional structure using Sybyl and Insight II packages. - Adept at structure-function relationship analysis (protein domain) based on primary sequences and PDB crystal structures. - Development of applications for genomic sequencing data, including algorithms and implementation. - Skilled at signature sequence analysis. Protein domains and protein family classification for protein and DNA sequences. - Expert at writing 3-tier applications development in microarray and sequence data analysis. - Experienced in development of computer applications for genomic data analysis. - Expert program writer for microarray data analysis. - Database design and implementation. | |
| Education | |
Microbiology Department, Texas Technological Institute | 2001 |
| Ph.D, Molecular Biology and Protein Chemistry, Pathobiology Department, | |
Computer and Information Science and Engineering Department, University of Washington | 2002 |
| M.S., M.S., Computer and Information Science | |
| KEY SUBJECT AREAS: Programming Languages, Database Management, Computer Architecture, Software Testing, Computation Algorithms, Data Structure and Algorithms, and Computer Architecture | |
Biology Department, Brigham Young University | 1994 |
| M.S., Biology | |
Biology Department,Brigham Young University | 1985 |
| B.S., Biology | |
| Computer Skills | |
| • | SYSTEMS - UNIX, Windows 95/98NT/2000, and Linux |
| • | LANGUAGES - Basic, C++, SQL, Java |
| • | DATABASES - Access, Oracle |
| • | APPLICATIONS - MS Office, Oracle Tools, SAS |
| Relevant Experience | |
| MOLECULAR BIOLOGY • Developed library cataloguing DNA Anaplasma marginale. • Researched and sequenced DNA of plamepsin genes. COMPUTER SCIENCE • Wrote web-based data management system in Java. • Wrote applications for HIV genome project, using Visual Basic. • Used artificial neural network to develop diagnoses applications. • Automated collect of kinetic data with use of unique program.. • Used Matlab to create a microarray transformation algorithm.. PROTEIN SCIENCE • Expressed, purified, and enzymatically assayed proteinases from lyme disease parasites. • Mutated in vitro plamesins, based on analysis of structure-function relationship. • Made molecular models of plasmepsins for structure-functions relationship analysis. • Created effective protocols for protein purification/quantification. • Designed effective protocols for protein purification. • Discovered three proteinase genes of P. falciparum. • Created kinetic assay for plamepsins. | |
| Employment Chronology | |
University of Notre Dame | 2001 - Present |
| Postdoctoral Associate | |
University of Notre Dame, College of Biology | 1995 - 2001 |
| Research Assistant | |
Academy of Biology and Natural Sciences | 1986 - 1995 |
| Research Scientist | |
Academy of Biology and Natural Sciences | 1985 - 1986 |
| Research Assistant | |
| Awards | |
| Fellowship, University of Notre Dame | |
| Professional Societies | |
| American Association for Biology Professionals American Society of Biology Teachers | |
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